Dare to look beyond the horizon
The Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM) is the largest biomedical and healthcare research centre at Université de Montréal and one of the largest in Canada.
The nucleus of all research activities at the CHUM, the Research Centre is a place where knowledge, expertise and innovation coexist. It is made up of multidisciplinary teams working together to improve the health of the public. Its researchers and students are committed to a translational approach in order to transform scientific knowledge into tangible benefits for patients.
The CRCHUM improves the health of adults through a high-quality academic research continuum which, by furthering our understanding of etiological and pathogenic mechanisms, fosters the development, implementation and assessment of new preventive, diagnostic and therapeutic strategies.
CRCHUM provides a training environment to ensure the development of new generations of researchers committed to research excellence.
The CRCHUM seeks to attain the highest standards of excellence in the development of new knowledge, in line with the hospital’s mission. As one of the hospital’s department, the CRCHUM seeks to play a major role in improving health care and health promotion. It fosters interdisciplinary exchanges and harmonizes laboratory research collaborations with patients and the population with a view to promoting health.
Research at the heart of a state-of-the-art university hospital
The CRCHUM administers all the research activities of the Centre hospitalier de l’Université de Montréal (CHUM) and forms an integral part of the hospital. Its director, Vincent Poitout, is also Director of Research at CHUM. This management structure promotes alignment of research activities with hospital operations.
Our research activities make a direct contribution to the five components of the CHUM mission, an ultra-specialized university hospital affiliated with the Université de Montréal: care, research, teaching, health promotion and assessment of health treatment technology and methods. CRCHUM research priorities are also aligned with the hospital’s five poles of excellence: Cancer, Neurosciences, Cardiometabolism, Transplantation and Musculoskeletal diseases.
Research continuum: patient to patient
The CRCHUM is one of the first to make full use of its entire research continuum: basic, clinical and population health research.
Providing fertile ground for effective translational research, this comprehensive approach has proven to be a major asset in accelerating the transformation of scientific knowledge into tangible benefits for patients and ultimately contributing to improved individual health management. Patients’ and the public’s health issues guide our scientific initiatives and mobilize our expertise to provide practical solutions for improving care and preventing disease.
The health issues of our patients inspire various types of studies that form part of a research continuum: understanding pathological mechanisms, studying new treatments, developing diagnostic tools, care practices and health services. The ultimate goal of this research is to meet patients’ needs and use this knowledge to improve care.
Basic research covers about 60 percent of CRCHUM activities. Almost 80 researchers and 400 students are involved, with recognized expertise in solid cancers, metabolic diseases, immune, infectious and inflammatory processes, as well as neurological diseases. Intersectorial niches are in full development, with additional expertise in the field of imaging and biomedical engineering.
At CRCHUM, clinical research accounted for more than 400 projects in 2015-2016. This research is firmly anchored in CHUM’s clinical focuses. Thus, the CRCHUM is a recognized player for conducting clinical trials in the cancer field, or in neuroscience, to name just two. CRCHUM also stands out for its strong evaluative clinical trials component focused directly on improving patient care at CHUM through thorough analysis of practices.
With almost 30 researchers in the area of population health, CRCHUM provides notable leadership to influence changes in clinical practices based on newly generated evidence. These changes centre on access to care and methods for managing chronic diseases, with active patient involvement, or disease prevention programs for various pathologies (cancer, infections, chronic diseases).
Reflecting an essential need to accelerate conversion of a discovery into a rapid, practical application to benefit patients and the population, translational research is a major component of biomedical research. For this reason, CRCHUM has placed this sector at the very centre of its mission and supports its development through adapted infrastructure close to patients, and through research programs that specifically target deployment of a continuum “from patient to laboratory to patient.”
Key positioning on a global scale
CRCHUM focuses its research priorities on six sectors of excellence, linked with the hospital’s activities. These research focuses are structured in a matrix to promote multidisciplinary exchanges.
Our research activities are supported by a dozen of state-of-the-art core facilities and services. Our specialized equipment offer personalized support that meets the research needs of researchers at the CHUM Research Centre as well as those of our industry- and university-based clients. They are at the heart of the innovative approaches developed by CRCHUM researchers.
A lively scientific forum
As the venue for a very active scientific life, dozens of conferences and scientific activities are held each week at CRCHUM, especially seminars, thesis defences and weekly CRCHUM conferences at which internationally renowned researchers present their latest work. CRCHUM also organizes prestigious events such as the Journée scientifique du CRCHUM [scientific day], with the participation of a Nobel Prize recipient.
Responsible research conduct
CRCHUM adheres to the policy on responsible research conduct established by the Fonds de recherche en santé du Québec (FRQS) and the Canadian Institutes of Health Research (CIHR). All research activities conducted in whole or in part at CHUM are benchmarked, listed and conducted in compliance with the highest standards of academic research.