The molecular basis of neuronal dysfunction in glaucoma: new insights

Version imprimable
April 13, 2017
Adriana Di Polo

For the CRCHUM conference taking place on April 21, 2017, Adriana Di Polo, professor in Neuroscience at the Université de Montréal and researcher at the CRCHUM, will present a conference on glaucoma and neuronal dysfunction.


Glaucoma is the leading cause of irreversible blindness, affecting >60 million people worldwide. There is no cure for glaucoma and current therapies are inadequate. Loss of vision in glaucoma results from the death of retinal ganglion cells, the neurons that convey visual information from the retina to the brain. A major roadblock towards developing effective therapeutics for glaucoma is that very little is known about the early pathological alterations that lead to retinal ganglion cell dysfunction and death. In this conference, we will discuss molecular mechanisms that regulate two fundamental features of early neuronal damage in glaucoma: dendrite retraction accompanied by synapse loss and axonal transport impairment. We will also discuss common neurodegenerative pathways between glaucoma and Alzheimer’s disease.

This conference will be presented in English.

Friday, April 21, 2017, at Noon.
Auditorium of the CRCHUM , R05.210 and R05.220
900 Saint-Denis Street, 5th floor 
Montreal (Quebec)  H2X 0A9

Adriana Di Polo, Ph.D.
Professor, Department of Neuroscience, Université de Montreal
Researcher, theme Neuroscience, CRCHUM

About CRCHUM Conferences

The CRCHUM Conferences are free weekly meetings featuring renowned scientific speakers from various disciplines. These conferences are accredited by the Royal College of Physicians and Surgeons of Canada as continuing professional development activities. The CRCHUM conferences are made possible thanks to the financial support of our partners: AstraZeneca, GSK, Lilly, Merck, Roche & Servier.

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Schedule of the Conferences at the CRCHUM (french)

Schedule of scientific activities at the CRCHUM (french)