Is there a need for anticoagulation therapy after myocardial infarction?

Version imprimable

Publication in spotlight



Anterior myocardial infarction (MI) with apical dysfunction is associated with an increased risk of left ventricular thrombus (LVT) formation and systemic embolism (SE). However, the role for prophylactic anticoagulation in current practice is a matter of debate. We conducted a systematic review of peer-reviewed original articles published September 21, in the Canadian Journal of Cardiology. We concluded that available studies lacked statistical power and are heterogeneous and that there is presently no compelling evidence for or against combining anticoagulation with standard therapy for post-MI patients with apical dysfunction after primary PCI, and inconsistent evidence supporting prophylaxis after thrombolysis. An appropriately powered randomized trial Guillemets anglaisis required to answer this clinically relevant question.

Dr Brian J. Potter, Interventional cardiologist and researcher at the CRCHUM

Read the study

Read the editorial



The aim of the Publications in spotlight section is to introduce you to recent publications by researchers and students of the CHUM Research Centre (CRCHUM). To submit a publication, send a 120-word text in lay terms, an image and the article which you co-authored to

Return to the archives